Objectives and primary approaches

The project objectives were as follows -

  • To produce a genetic map with markers spaced at approximately 20 centiMorgan intervals over at least 90% of the pig genome.
  • To produce a physical map with at least one distal and one proximal landmark locus mapped on each porcine chromosome arm and also genetically mapped.
  • To develop a flow karyotype for the pig based on FACS sorted chromosomes.
  • To develop PCR based techniques to enable rapid genotyping for polymorphic markers.
  • To evaluate synteny conservation between pigs, man, mice and cattle.
  • To develop and evaluate the statistical techniques required to analyse data from QTL mapping experiments and to plan and initiate the mapping of QTLs in the pig.
 
copyright Roslin Institute 2002